daf-16/FOXO blocks adult cell fate in Caenorhabditis elegans dauer larvae via lin-41/TRIM71
Matthew J. Wirick, Allison R. Cale, Isaac T. Smith, Amelia F. Alessi, Margaret R. Starostik, Liberta Cuko, Kyal Lalk, Mikayla N. Schmidt, Benjamin S. Olson, Payton M. Salomon, Alexis Santos, Axel D. Schmitter-Sánchez, Himani Galagali, Kevin J. Ranke, Payton Wolbert, , Xantha Karp
This study shows that daf-16/FOXO promotes multipotency in C. elegans dauer larvae by upregulating lin-41/TRIM71, which blocks premature adult cell fate markers.
PLoS Genetics · Nov 15, 2021Peer-reviewedGenetics