A TLR7 Agonist Conjugated to a Nanofibrous Peptide Hydrogel as a Potent Vaccine Adjuvant
Erin M. Euliano, Brett H. Pogostin, Anushka Agrawal, Marina H. Yu, Tsvetelina H. Baryakova, Tyler P. Graf, Alyssa A. Kunkel, Kiana A. Cahue, Jeffrey D. Hartgerink, Kevin J. McHugh
This paper conjugates a TLR7 agonist to a peptide hydrogel to create a vaccine adjuvant that produces antibody titers similar to alum and a more balanced Th1/Th2 immune response.
Advanced Healthcare Materials · Oct 25, 2024Peer-reviewedBioengineering