Brett H. Pogostin

This study uses AI to rapidly develop thermostable mRNA vaccines that maintain bioactivity at high temperatures and can be delivered via microneedle patches.

This study investigates how interhelical interactions guide the assembly of collagen mimetic peptides into D-periodic fibrils, nanotubes, and nanosheets.

This study develops SABER hydrogels that extend drug release and therapeutic effect for small molecules and biologics in preclinical models.

This paper demonstrates that Dopa crosslinking with lysine covalently stabilizes collagen mimetic peptides and their assemblies, enhancing thermal stability for biomedical applications.

This paper conjugates a TLR7 agonist to a peptide hydrogel to create a vaccine adjuvant that produces antibody titers similar to alum and a more balanced Th1/Th2 immune response.

This paper designs a collagen heterotrimer with high folding specificity and reports its faster folding rate compared to other systems.