Marina H. Yu

This study develops SABER hydrogels that extend drug release and therapeutic effect for small molecules and biologics in preclinical models.

This paper develops a prodrug system for targeted colonic delivery of budesonide using gut commensals, showing improved drug localization and reduced systemic side effects.

This paper conjugates a TLR7 agonist to a peptide hydrogel to create a vaccine adjuvant that produces antibody titers similar to alum and a more balanced Th1/Th2 immune response.

This paper describes a novel vaccination platform using crosslinking polymers to enhance humoral immunity and dendritic cell activation in lymph nodes without adjuvants.