ImmunologyImmunityPeer-reviewed
Activation of intestinal immunity by pathogen effector-triggered aggregation of lysosomal TIR-1/SARM1
Samantha Y. Tse, Khursheed Alam Wani, Nicholas Peterson…·Read Pukkila-Worley
The paper identifies lysosomal TIR-1/SARM1 as a sensor for oxidative stress induced by pathogenic bacteria, activating intestinal immunity in C. elegans.
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