Author

Nicholas Peterson

University of Massachusetts Chan Medical SchoolORCID 0000-0003-4157-8119Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Read Pukkila-WorleyiD· 3 shared Khursheed Alam WaniiD· 2 shared Adebanjo Adedoja· 1 shared Akshay AlaghattaiD· 1 shared Alexander A. SoukasiD· 1 shared Amanda Page· 1 shared Armen I. YerevanianiD· 1 shared Daniel BolleniD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersGenetics

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3 papers

Recent·Most cited

GeneticsPLoS GeneticsPeer-reviewedOct 30, 2026

kri-1/KRIT1 restrains skn-1/NRF2 activation to promote innate immune and lipid homeostasis

Akshay Alaghatta, Samantha Tse-Kang, Daniel Bollen…·Read Pukkila-Worley

This study identifies kri-1/KRIT1 as a regulator that limits skn-1/NRF2 activity to control immune responses and lipid homeostasis in C. elegans, supporting reproductive health.

DOI 10.1371/journal.pgen.1012166

C. elegansexperimental assay

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ImmunologyImmunityPeer-reviewedSep 18, 2024

Activation of intestinal immunity by pathogen effector-triggered aggregation of lysosomal TIR-1/SARM1

Samantha Y. Tse, Khursheed Alam Wani, Nicholas Peterson…·Read Pukkila-Worley

The paper identifies lysosomal TIR-1/SARM1 as a sensor for oxidative stress induced by pathogenic bacteria, activating intestinal immunity in C. elegans.

19 citations

C. elegansproteomics

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GeneticseLifePeer-reviewedJul 14, 2023

Ether Lipid Biosynthesis Promotes Lifespan Extension and Enables Diverse Prolongevity Paradigms

Lucydalila Cedillo, Sainan Li, Fasih M. Ahsan…·Alexander A. Soukas

This study identifies ether lipid biosynthesis as a key pathway mediating the longevity benefits of biguanides like metformin in C. elegans.

42 citations

C. elegansexperimental assay

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