Memory T and B cells with recognition of avian influenza hemagglutinins are poorly responsive to existing seasonal influenza vaccines
Christopher A. Gonelli, Marios Koutsakos, Robyn Esterbauer, Ming Z. M. Zheng, Yee‐Chen Liu, Amanda Zin, Lara S. U. Schwab, Danielle Tilmanis, Malet Aban, Aeron C. Hurt, Stephen John Kent, Jennifer A. Juno, Adam K. Wheatley
The paper quantifies pre-existing human B cell responses to avian influenza H5 and H7 hemagglutinins and shows limited boosting by seasonal vaccines.
bioRxiv · Apr 28, 2025 · PreprintImmunology