The gamma-Protocadherins regulate the survival of GABAergic interneurons during developmentally-regulated cell death.
Candace H. Carriere, Wendy Xueyi Wang, Anson D. Sing, Ádám Fekete, Brian E. Jones, Yohan Yee, Jacob Ellegood, Harinad B. Maganti, Lola Awofala, Julie Marocha, Amar Aziz, Lu‐Yang Wang, Jason P. Lerch, Julie L. Lefebvre
This study shows that gamma-Protocadherins are essential for the survival of GABAergic interneurons during development, preventing excessive apoptosis and ensuring proper inhibitory network formation.
Journal of Neuroscience · Oct 15, 2020Peer-reviewedNeuroscience