Author

Amber C. Nobles

University of Alabama at Birmingham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Albert R. La SpadaiD· 1 shared Allison BirnbaumiD· 1 shared Amy W. Huang· 1 shared Anastasia Gromova· 1 shared Constanza J. CortésiD· 1 shared Dalton C. PattersoniD· 1 shared Eleanor A. LiuiD· 1 shared Elizabeth FernándeziD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperNeuroscience

Albert R. La SpadaORCID

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2 papers

Recent·Most cited

Rab27b promotes lysosomal function and alpha-synuclein clearance in neurons

Kasandra Scholz, Rudradip Pattanayak, Roschongporn Ekkatine, Frank Sanders Pair, Amber C. Nobles, William J. Stone, Talene A. Yacoubian

This study shows Rab27b enhances lysosomal function and reduces alpha-synuclein accumulation in neurons, suggesting it as a therapeutic target for synucleinopathies.

Journal of Neuroscience · Feb 18, 2025Peer-reviewedNeuroscience

Skeletal Muscle TFEB Signaling Promotes Central Nervous System Function and Reduces Neuroinflammation during Aging and Neurodegenerative Disease

Ian Matthews, Allison Birnbaum, Anastasia Gromova, Amy W. Huang, Kailin Liu, Eleanor A. Liu, Kristen Coutinho, Megan McGraw, Dalton C. Patterson, Macy T. Banks, Amber C. Nobles, Nhat Nguyen, Gennifer E. Merrihew, Lu Wang, Eric Baeuerle, , Constanza J. Cortés

This study shows that enhancing skeletal muscle TFEB signaling reduces neuroinflammation and tau pathology in aging and neurodegenerative disease models.

Cell Reports · Nov 1, 2023Peer-reviewedNeuroscience