Allison Birnbaum

This study shows that long-term voluntary exercise in 5xFAD mice leads to limited molecular changes in the hippocampus that do not translate into significant neuroprotection.

This study compares cytokine responses in male and female mice to TFEB overexpression and voluntary wheel running, revealing sex-based differences in exercise-induced inflammation.

The paper evaluates changes in glia-neuron communication in 3xTg-AD mice hippocampus at 6 and 12 months, finding increased dysregulation and 23 AD-associated ligand-receptor pairs.

This study shows that enhancing the muscle-to-brain axis in Alzheimer's disease mice reduces amyloid plaques and improves cognitive function through neurotrophic and synaptic signaling.

This study shows that enhancing skeletal muscle TFEB signaling reduces neuroinflammation and tau pathology in aging and neurodegenerative disease models.

This study shows FOXO maintains neuromuscular junction integrity during aging in Drosophila by repressing MAPK signaling.

This study investigates age-related changes in FOXO transcription factor gene targeting in Drosophila melanogaster using ChIP-Seq, revealing a decline in FOXO-bound genes and shifts in targeted biological processes with age.

This study identifies a physical and genetic interaction between dFOXO and Kr-h1 in Drosophila, showing that Kr-h1 represses lipolysis by regulating adipose lipase brummer transcription.