Lu Wang

This study identifies glutathione deficiency as a key factor in age-related dopamine neuron loss and links it to lifespan in Drosophila, with implications for human Parkinson's disease.

This study shows that enhancing skeletal muscle TFEB signaling reduces neuroinflammation and tau pathology in aging and neurodegenerative disease models.

The paper analyzes lifespan variation in wild yeast isolates to identify genetic and environmental factors shaping replicative lifespan and cellular processes involved in aging.

This study shows that calorie restriction in mice increases microbial diversity and prevents age-related microbiome changes, maintaining a younger microbial and metabolite profile.