Intranasal Anti-CD3 Antibody Treatment Attenuates Post-COVID Neuroinflammation and Enhances Hippocampal Neurogenesis and Cognitive Function in Mice
Peiwen Lu, Saef Izzy, Patrick da Silva, Harm Tjebbe Imkamp, Jonathan R Christenson, Taha Yahya, Maryam Hazim Al Mansi, Amir Alawi, Thaís Garcias Moreira, Michelle Monje, Howard L. Weiner, Akiko Iwasaki
This study shows nasal anti-CD3 antibody treatment reduces neuroinflammation, enhances neurogenesis, and improves cognitive function in a mouse model of Long COVID.
bioRxiv · Apr 16, 2026 · PreprintImmunology