SET1/MLL complexes control transcription independently of H3K4me3
Ho Yu Alan Au, Aleksander Szczurek, Inge de Krijger, Nianna Kjelstrup-Osorio, Amy L. Hughes, Anna Lastuvkova, Michiel Vermeulen, Robert J. Klose
The paper identifies a new SET1B complex and shows SET1/MLL complexes control transcription independently of H3K4me3 by counteracting promoter-proximal termination and supporting transcription burst size.
bioRxiv · Dec 10, 2025 · PreprintGenomics