Author

Emilia Dimitrova

University of OxfordORCID 0000-0001-5669-1240Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 3 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Assay:ChIP-seq· 2 Research Focus:protein structure prediction· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Robert J. KloseiD· 4 shared Angelika FeldmanniD· 3 shared Anna Lastuvkova· 2 shared Aleksander SzczurekiD· 1 shared Álvaro Rada-IglesiasiD· 1 shared Amador GallardoiD· 1 shared Amy L. Hughes· 1 shared Anne H. TurberfieldiD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersMolecular Biology

Robert J. KloseORCID

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4 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedFeb 9, 2023

A CpG island-encoded mechanism protects genes from premature transcription termination

Amy L. Hughes, Aleksander Szczurek, Jessica R. Kelley…·Robert J. Klose

The paper identifies a CpG island-encoded mechanism where SET1 complexes interact with WDR82 to prevent premature transcription termination, distinguishing genic from non-genic transcription.

59 citationstop 3%

DNA methylationChIP-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJul 26, 2022

Polycomb repression during S/G2 phases restrain initiation of cell differentiation to the G1 phase of the cell cycle

Helena G. Asenjo, María Alcázar‐Fabra, Mencía Espinosa-Martínez…·David Landeira

The paper shows that Polycomb repression during S/G2 phases restricts differentiation gene activation, allowing it to occur primarily in G1 phase in mouse ESCs.

DOI 10.1101/2022.07.26.501502

mousebulk RNA-seq

𝕏 PostBluesky

Molecular BiologybioRxivPreprintNov 4, 2021

Distinct roles for CDK-Mediator in controlling Polycomb-dependent chromosomal interactions and priming genes for induction

Emilia Dimitrova, Angelika Feldmann, Robin H. van der Weide…·Robert J. Klose

The paper investigates the role of CDK-Mediator in gene regulation, finding it essential for Polycomb-dependent chromosomal interactions and gene priming during differentiation through distinct mechanisms.

2 citations

mouseChIP-seq

𝕏 PostBluesky

Developmental BiologyeLifePeer-reviewedMay 29, 2018

FBXL19 recruits CDK-Mediator to CpG islands of developmental genes to prime them for activation during lineage commitment

Emilia Dimitrova, Takashi Kondo, Angelika Feldmann…·Robert J. Klose

The paper identifies FBXL19 as a CpG island-binding protein that recruits CDK-Mediator to developmental gene promoters in mouse ES cells, priming them for activation during lineage commitment.

29 citations

mouseexperimental assay

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