Author

Anne H. Turberfield

University of OxfordORCID 0000-0002-9541-4542Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Robert J. KloseiD· 3 shared Anna Lastuvkova· 2 shared Neil P. BlackledgeiD· 2 shared Aleksander SzczurekiD· 1 shared Amy L. Hughes· 1 shared Emilia DimitrovaiD· 1 shared Emma L. Findlater· 1 shared Hamish W. KingiD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersMolecular Biology

Robert J. KloseORCID

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3 papers

Recent·Most cited

A CpG island-encoded mechanism protects genes from premature transcription termination

Amy L. Hughes, Aleksander Szczurek, Jessica R. Kelley, Anna Lastuvkova, Anne H. Turberfield, Emilia Dimitrova, Neil P. Blackledge, Robert J. Klose

The paper identifies a CpG island-encoded mechanism where SET1 complexes interact with WDR82 to prevent premature transcription termination, distinguishing genic from non-genic transcription.

Nature Communications · Feb 9, 2023Peer-reviewedMolecular Biology

BAP1 constrains pervasive H2AK119ub1 to control the transcriptional potential of the genome

Nadezda A. Fursova, Anne H. Turberfield, Neil P. Blackledge, Emma L. Findlater, Anna Lastuvkova, Miles K. Huseyin, Paula Dobrinić, Robert J. Klose

The paper shows that BAP1 limits H2AK119ub1 levels, which affects gene expression and Polycomb complex function, revealing a general mechanism for controlling transcriptional potential.

bioRxiv · Nov 13, 2020Molecular Biology

KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity

Anne H. Turberfield, Takashi Kondo, Manabu Nakayama, Yoko Koseki, Hamish W. King, Haruhiko Koseki, Robert J. Klose

This study shows KDM2 proteins repress transcription from CpG island promoters without relying on their histone demethylase activity.

Nucleic Acids Research · Jul 3, 2019Peer-reviewedMolecular Biology