Author

Amy Shelton

Genentech

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Kerstin SeideliD· 2 shared Lluc MosteiroiD· 2 shared Adel ElSohly· 1 shared Alexis ScherliD· 1 shared Casper C. HoogenraadiD· 1 shared Cecile C. de la Cruz· 1 shared Charisa CottonhamiD· 1 shared Chris Siebel· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPhysiology

Kerstin SeidelORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Hypothalamic oligodendrocytes regulate systemic energy balance through Notch-dependent state transitions

Simona Hankeová, Margaret Hayne, Mathijs P. Verhagen, Greg Farber, Michelle Dourado, Dewakar Sangaraju, Kayla Lee, Praveen Krishnamoorthy, Ronal Peralta, Kerstin Seidel, Kai Barck, Amy Shelton, Manal Sadek, Pamela Chan, Adel ElSohly, , Lluc Mosteiro

This study identifies Notch signaling in hypothalamic oligodendrocytes as a regulator of systemic energy balance, showing that inhibiting Notch ligands leads to weight loss and metabolic changes.

bioRxiv · Jul 31, 2026 · PreprintPhysiology

Notch signaling maintains a progenitor-like subclass of hepatocellular carcinoma

Kerstin Seidel, Robert Piskol, Thi Thu Thao Nguyen, Amy Shelton, Charisa Cottonham, Cecile C. de la Cruz, Joseph Castillo, Jesse Garcia, Udi Segal, Mark A. Merchant, Yeqing Angela Yang, Jasmine Chen, Musa Ahmed, Alexis Scherl, Rajesh Vij, , Chris Siebel

This study identifies Notch-dependent progenitor-like HCCs that regress upon Notch inhibition, revealing a therapeutic target in a poor-prognosis subgroup.

bioRxiv · Dec 13, 2024 · PreprintCancer Biology