Low-affinity binding motif in microtubule plus-end condensates specializes microtubule function
Madhurima Choudhury, Federico Uliana, Tarik Grubić, Mateusz P. Czub, Ana-Maria Farcas, Michel Olivier Steinmetz, Yves Barral
The paper identifies a low-affinity KDK motif in Kar9 that specializes +TIP body function by modulating microtubule dynamics through multivalent interactions with Bik1.
bioRxiv · Jun 27, 2026 · PreprintCell Biology