Anandita Rajpurohit

This study investigates the genetic regulation of miRNA expression in human brain tissues and identifies miRNAs associated with psychiatric and neurodegenerative disorders.

The paper performs transcriptomic analysis of the human habenula and identifies molecular changes associated with schizophrenia risk and illness state.

The paper uses hiPSC transcriptomics to study neuronal differentiation and maturation across multiple conditions and develops a tool to estimate neuronal maturity.

This study evaluates biases in small RNA sequencing methods, showing that UMIs improve accuracy and highlighting limitations in current miRNA and isomiR quantification.

The paper identifies regional differences in gene expression and regulation in hippocampus and dorsolateral prefrontal cortex across development and in schizophrenia using RNA-seq data from 900 samples.

The paper characterizes nuclear and cytoplasmic transcriptomes in human cortex development and finds increased nuclear retention in mature brain, linked to psychiatric disease gene regulation.

This study shows that BDNF from promoters I and II is essential for maternal behavior in female mice by regulating oxytocin expression and signaling through TrkB in oxytocin neurons.

The paper introduces xMD-miRNA-seq to obtain in vivo miRNA expression from colon epithelial cells using FFPE tissues, showing cell-specific miRNA profiles comparable to other epithelial sources.