Taeyoung Hwang

The paper identifies a gene expression program in active neurons that supports sustained network activity, distinct from immediate early gene responses and enriched for excitability regulators.

This study demonstrates that allele-specific antisense oligonucleotides can rescue ATAD3A-associated developmental defects in zebrafish by reducing mutant transcripts.

This study investigates the genetic regulation of miRNA expression in human brain tissues and identifies miRNAs associated with psychiatric and neurodegenerative disorders.

This study shows that calcium-permeable AMPA receptors (CP-AMPARs) in PV interneurons reduce their feature selectivity, and removing them increases selectivity in visual cortex and hippocampus.

The paper introduces MPRNA-IP, a method to dissect RNA-protein interactions in vivo using custom RNA pools and statistical models to identify binding domains and structures.

The paper evaluates the RNA-dependence of PRC2 chromatin binding in human pluripotent stem cells using optimized rChIP-seq and mutant analyses, supporting original findings.

The paper characterizes nuclear and cytoplasmic transcriptomes in human cortex development and finds increased nuclear retention in mature brain, linked to psychiatric disease gene regulation.

The paper identifies Tug1 as essential for male fertility, showing it has three distinct regulatory activities: a cis DNA repressor, a trans-acting lncRNA, and a conserved peptide affecting mitochondrial function.