Author

Meinusha Govindarajan

University Health Network

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Assay:proteomics· 5 Research Focus:differential expression· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Matthew WaasiD· 5 shared Thomas KislingeriD· 5 shared Amanda KhooiD· 3 shared Vladimir IgnatchenkoiD· 3 shared Brian P. MainiD· 2 shared Julius O. NyalwidheiD· 2 shared Laurie AillesiD· 2 shared Lydia LiuiD· 2 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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5 shared papersCancer Biology

Matthew WaasORCID

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Author profile →

5 papers

Recent·Most cited

Ancestry-Dependent Immunologic and Prognostic Effects Characterize the Prostate Cancer Urinary Proteome

Annie Ha, Jaron Arbet, Zhuyu Qiu, Amanda Khoo, Brian P. Main, Meinusha Govindarajan, Matthew Waas, Stanley K. Liu, Oliver John Semmes, Julius O. Nyalwidhe, Paul Christopher Boutros, Thomas Kislinger

The paper quantifies urinary proteome differences between Black and White prostate cancer patients, finding immune pathway dysregulation and aggressive cancer features in Black patients after controlling for age, PSA, and cISUP.

JNCI Journal of the National Cancer Institute · Sep 11, 2026Peer-reviewedCancer Biology

Pan-cancer N-glycoproteomic atlas of patient derived xenografts uncovers FAT2 as a therapeutic target for head and neck cancers

Meinusha Govindarajan, Salvador Mejia‐Guerrero, Shawn C. Chafe, Shahbaz Khan, Wei Shi, Matthew Waas, Martín A. Rossotti, Amanda Khoo, Lydia Liu, Vladimir Ignatchenko, Simona Principe, Lusia Sepiashvili, Greg Hussack, Nazanin Tatari, Chitra Venugopal, , Thomas Kislinger

This paper uses N-glycoproteomics to analyze patient-derived xenografts, identifies FAT2 as a therapeutic target for head and neck cancers, and validates its role in tumor growth and CAR T cell activity.

Cell Reports Medicine · Jan 23, 2026Peer-reviewedCancer Biology

Mapping lineage and functional diversity in the high-risk human mammary epithelium

Matthew Waas, Bowen Zhang, Meinusha Govindarajan, Pirashaanthy Tharmapalan, Abhijith Kuttanamkuzhi, Olivia Drummond Guy, Michael Woolman, Hal K. Berman, Paul D. Waterhouse, Rama Khokha, Thomas Kislinger

The paper profiles proteomic and functional features of mammary epithelial cells in high-risk women, showing how clinical factors influence cellular composition and tumor risk.

bioRxiv · Jan 13, 2026 · PreprintCancer Biology

Surface proteomics reveals arginine metabolism as a vulnerability in high grade serous ovarian cancer

Meinusha Govindarajan, Matthew Waas, Salvador Meija-Guerrero, Brian Lin, Tianyi Ling, Ximing Li, Vladimir Ignatchenko, Anastasia N. Tikhonova, Courtney L. Jones, Laurie Ailles, Thomas Kislinger

This study identifies SLC7A1 and arginine metabolism as a therapeutic vulnerability in high-grade serous ovarian cancer through surface proteomics and functional analysis.

bioRxiv · Sep 2, 2025 · PreprintCancer Biology

Prostate Cancer Reshapes the Secreted and Extracellular Vesicle Urinary Proteomes

Amanda Khoo, Meinusha Govindarajan, Zhuyu Qiu, Lydia Liu, Vladimir Ignatchenko, Matthew Waas, Andrew M. Macklin, Alexander F. A. Keszei, Sarah Neu, Brian P. Main, Lifang Yang, Raymond S. Lance, Michelle R. Downes, Oliver John Semmes, Danny Vesprini, , Thomas Kislinger

The paper quantifies secreted and extracellular vesicle (EV) urinary proteomes in men with and without prostate cancer, showing their stability and utility in distinguishing malignant from benign lesions.

Nature Communications · Jun 13, 2024Peer-reviewedSystems Biology