Author

Andrew O. Kearney

Northwestern University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Edward Benjamin ThorpiD· 2 shared Esther LiuiD· 2 shared Jennie J. LiniD· 2 shared Johnson Y. Yang· 2 shared Matthew WrightiD· 2 shared Amal Dadi· 1 shared Grant D. BarishiD· 1 shared Hanrui ZhangiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenomics

Edward Benjamin ThorpORCID

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2 papers

Recent·Most cited

APOL1 G1 and G2 risk alleles modulate severity of diet-induced obesity in a transgenic mouse model

Andrew O. Kearney, Johnson Y. Yang, Esther Liu, Matthew Wright, Margaret E. Chen, Jiayi Kong, Grant D. Barish, Edward Benjamin Thorp, Jennie J. Lin

This study shows that APOL1 G1 and G2 risk alleles affect diet-induced obesity severity differently in male and female transgenic mice.

bioRxiv · Dec 25, 2025 · PreprintGenomics

G1 and G2 ApolipoproteinL1 modulate macrophage inflammation and lipid accumulation through the polyamine pathway

Esther Liu, Matthew Wright, Andrew O. Kearney, Tiffany N. Caza, Johnson Y. Yang, Valerie Garcia, Amal Dadi, Shuta Ishibe, Navdeep S. Chandel, Hanrui Zhang, Edward Benjamin Thorp, Jennie J. Lin

This study shows G1 and G2 APOL1 variants increase macrophage inflammation and lipid accumulation via the polyamine pathway, which can be inhibited by DFMO.

bioRxiv · Jun 6, 2025 · PreprintCell Biology