Author

Johnson Y. Yang

Northwestern University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew O. Kearney· 2 shared Edward Benjamin ThorpiD· 2 shared Esther LiuiD· 2 shared Jennie J. LiniD· 2 shared Matthew WrightiD· 2 shared Amal Dadi· 1 shared Ashby J. MorrisoniD· 1 shared Caroline Valdez· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenomics

Andrew O. Kearney

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

APOL1 G1 and G2 risk alleles modulate severity of diet-induced obesity in a transgenic mouse model

Andrew O. Kearney, Johnson Y. Yang, Esther Liu, Matthew Wright, Margaret E. Chen, Jiayi Kong, Grant D. Barish, Edward Benjamin Thorp, Jennie J. Lin

This study shows that APOL1 G1 and G2 risk alleles affect diet-induced obesity severity differently in male and female transgenic mice.

bioRxiv · Dec 25, 2025 · PreprintGenomics

G1 and G2 ApolipoproteinL1 modulate macrophage inflammation and lipid accumulation through the polyamine pathway

Esther Liu, Matthew Wright, Andrew O. Kearney, Tiffany N. Caza, Johnson Y. Yang, Valerie Garcia, Amal Dadi, Shuta Ishibe, Navdeep S. Chandel, Hanrui Zhang, Edward Benjamin Thorp, Jennie J. Lin

This study shows G1 and G2 APOL1 variants increase macrophage inflammation and lipid accumulation via the polyamine pathway, which can be inhibited by DFMO.

bioRxiv · Jun 6, 2025 · PreprintCell Biology

Endocardial/endothelial angiocrines regulate cardiomyocyte development and maturation and induce features of ventricular non-compaction

Siyeon Rhee, David T. Paik, Johnson Y. Yang, Danielle Nagelberg, Ian M. Williams, Lei Tian, Robert Roth, Mark Chandy, Jiyeon Ban, Nadjet Belbachir, Seokho Kim, Hao Zhang, Ragini Phansalkar, Ka Man Wong, Devin A. King, , Kristy Red‐Horse

This study identifies angiocrine factors secreted by endocardial and endothelial cells that regulate cardiomyocyte development and maturation, contributing to ventricular non-compaction in Ino80-deficient mouse hearts.

European Heart Journal · May 16, 2021Peer-reviewedDevelopmental Biology