Very long-chain ceramides in muscle associate with insulin resistance independent of obesity
Søren Madsen, Harry B. Cutler, Kristen C. Cooke, Meg Potter, Jasmine X. Y. Khor, Christoph D Rau, Stewart W. C. Masson, Anna Howell, Zora D. Modrusan, Anthony Simon Don, Jacqueline Stöckli, Alexis Díaz‐Vegas, David Ernest James
The paper identifies very long-chain ceramides in muscle as independently associated with insulin resistance, separate from adiposity effects, using genetic variation in mice.
bioRxiv · Mar 4, 2025 · PreprintSystems Biology