Anthony Simon Don

This study identifies TAM as a bacterial phospholipid transport system, revealing its structure and mechanism for lipid delivery to the outer membrane.

This study quantifies and localizes new myelin lipid synthesis in mice using deuterium oxide and mass spectrometry during remyelination.

This study uses in vivo deuteration and lipidomics to show that myelin lipid turnover varies by lipid class and brain region, with reduced renewal rates in older mice.

This study identifies PRDM9 as a factor promoting survival of drug-tolerant persister cells in glioblastoma through metabolic rewiring and cholesterol biosynthesis.

The paper identifies very long-chain ceramides in muscle as independently associated with insulin resistance, separate from adiposity effects, using genetic variation in mice.

This study shows that mice lacking CerS2 in oligodendrocytes develop myelin instability, microglial activation, and early lethality due to reduced C22-C24 sphingolipids.

This study shows that SphK2 is essential for remyelination after demyelination and myelin maintenance with age, as SphK2 deficiency leads to greater oligodendrocyte loss and thinner myelin.