Ewing Sarcoma Breakpoint Region 1 (EWSR1) protein binds to the non-structural protein-2 and the non-coding regions of the Chikungunya virus genome to inhibit the virus replication
Shivani Balyan, Anshula Sharma, Devendra Sharma, Deepti Jain, Sudhanshu Vrati
This study identifies EWSR1 as a host protein that inhibits Chikungunya virus replication by binding viral RNA and the nsP2 protein, reducing viral RNA synthesis and titers.
Journal of Virology · Jul 21, 2026Peer-reviewedMicrobiology