Sudhanshu Vrati

JEV helicase targets host MTOC and participates in the organization of pericentriolar viroplasm

This study identifies JEV helicase's role in targeting host MTOCs and forming pericentriolar viroplasm, revealing centrosome-cytoskeleton interactions in viral infection.

Ewing Sarcoma Breakpoint Region 1 (EWSR1) protein binds to the non-structural protein-2 and the non-coding regions of the Chikungunya virus genome to inhibit the virus replication

This study identifies EWSR1 as a host protein that inhibits Chikungunya virus replication by binding viral RNA and the nsP2 protein, reducing viral RNA synthesis and titers.

AGPAT1 is a novel Chikungunya virus receptor on human cells

This study identifies AGPAT1 as a novel receptor for Chikungunya virus on human cells, showing its role in virus binding, uptake, and replication.

Endophilin mediated endocytosis and Epidermal growth factor receptor govern Japanese encephalitis virus entry and infection in neuronal cells

This study identifies Endophilin and EGFR as essential host factors for Japanese encephalitis virus entry and infection in neuronal cells through clathrin-independent endocytosis.

Emetine dihydrochloride inhibits Chikungunya virus nsP2 helicase and shows antiviral activity in the cell culture and mouse model of virus infection

This paper identifies Emetine dihydrochloride as a potent antiviral against Chikungunya virus, showing reduced viremia and absence of joint swelling in mice.

Identification and In Silico Characterization of Novel lncRNAs Associated with Dengue Infection

The paper identifies 65 novel lncRNAs differentially expressed in dengue infection and characterizes their potential regulatory roles through bioinformatics analysis.

Identification and Characterization of Novel Metagenome Assembled Uncultivated Virus Genomes from Human Gut

The paper identifies and characterizes novel metagenome-assembled virus genomes from the human gut, revealing new species and functional genes.

Japanese Encephalitis Virus Infected Microglial Cells Secrete Exosomes Containing let-7a/b that Facilitate Neuronal Damage via Caspase Activation

The paper identifies let-7a/b miRNAs in JEV-infected microglia and shows they promote neuronal damage via exosome-mediated caspase activation.