This study identifies BPA-induced ubiquitinome changes in trophoblast cells, showing PPAR-alpha hyper-ubiquitination disrupts migration and may contribute to placental dysfunction.

bioRxiv · May 8, 2026 · PreprintBiochemistry

AGPAT1 is a novel Chikungunya virus receptor on human cells

Brohmomoy Basu, Debapriyo Sarmadhikari, Anshula Sharma, Shailendra Asthana, Manjula Kalia, Sudhanshu Vrati

This study identifies AGPAT1 as a novel receptor for Chikungunya virus on human cells, showing its role in virus binding, uptake, and replication.

Journal of Virology · Feb 17, 2026Peer-reviewedMicrobiology

Cholesterol-activated VapC12 toxin modulates growth and drug susceptibility in Mycobacterium tuberculosis

Zohra Hashmi, Shivendra Pratap Singh, Sakshi Talwar, Abhin Kumar Megta, Mitul Srivastava, Debapriyo Sarmadhikari, Prabhakar Babele, Sourabh Kundu, Taruna Sharma, Chandresh Sharma, Shailendra Asthana, Vengadesan Krishnan, Amit Kumar Pandey

This study identifies a cholesterol-binding motif in the VapC12 toxin of M. tuberculosis and shows that cholesterol activates the toxin, reducing bacterial growth and antibiotic susceptibility.

bioRxiv · Oct 10, 2025 · PreprintMicrobiology