Molecular BiologybioRxivPreprint
Unified function of FACT in mammalian chromatin replication and transcription, dissolving and restoring nucleosomes to counteract genome aggregation
R. Frater, Rikke Rejnholdt Jensen, Joaquim Ollé-López…·Anja Groth
This study shows that FACT is essential for chromatin replication and transcription by disrupting and reassembling nucleosomes, preventing genome aggregation.