Identification of neural oscillations and epileptiform changes in human brain organoids
Ranmal Aloka Samarasinghe, Osvaldo A. Miranda, Jessie E. Buth, Simon A. Mitchell, Isabella Ferando, Momoko Watanabe, Thomas F. Allison, Arinnae Kurdian, Namie N. Fotion, Michael J. Gandal, Peyman Golshani, Kathrin Plath, William E. Lowry, Jack M. Parent, István Módy, Bennett G. Novitch
This study identifies neural oscillations and epileptiform changes in human brain organoids derived from MECP2 mutant patients using calcium imaging and extracellular recordings.
Nature Neuroscience · Aug 23, 2021Peer-reviewedNeuroscience