Author

Jessie E. Buth

University of California, Los AngelesORCID 0000-0001-9709-4274Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Developmental Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Michael J. GandaliD· 4 shared Bennett G. NovitchiD· 3 shared Kathrin PlathiD· 2 shared Momoko WatanabeiD· 2 shared Osvaldo A. MirandaiD· 2 shared A. Kimberley McAllisteriD· 1 shared Amanda J. CollieriD· 1 shared Amander T. ClarkiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersNeuroscience

Michael J. GandalORCID

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Author profile →

5 papers

Recent·Most cited

Translatome profiling reveals opposing alterations in inhibitory and excitatory neurons of Fragile X mice and identifies EPAC2 as a therapeutic target.

Anand Suresh, Nazim Kourdougli, Toshihiro Nomura, Jessie E. Buth, Soledad Miranda‐Rottmann, Carlos Andrés Sánchez-León, Michelle W. Wu, Sofia M. Nelson, Lauren T. Wall, Anne Tran, Roberto Araya, Anis Contractor, Michael J. Gandal, Carlos Portera‐Cailliau

Neuron · May 18, 2026Peer-reviewedNeuroscience

Foxp1 acts upstream of Vegfa, suppresses cortical angiogenesis, and promotes hypoxia in radial glia.

Caroline Alayne Pearson, Jessie E. Buth, Michael R.M. Harrison, Margaret Elizabeth Ross, Bennett G. Novitch

This study shows that Foxp1 loss increases angiogenesis and hypoxia in radial glia, altering their metabolic state and neurogenic capacity.

bioRxiv · Oct 17, 2022 · PreprintDevelopmental Biology

Identification of neural oscillations and epileptiform changes in human brain organoids

Ranmal Aloka Samarasinghe, Osvaldo A. Miranda, Jessie E. Buth, Simon A. Mitchell, Isabella Ferando, Momoko Watanabe, Thomas F. Allison, Arinnae Kurdian, Namie N. Fotion, Michael J. Gandal, Peyman Golshani, Kathrin Plath, William E. Lowry, Jack M. Parent, István Módy, Bennett G. Novitch

This study identifies neural oscillations and epileptiform changes in human brain organoids derived from MECP2 mutant patients using calcium imaging and extracellular recordings.

Nature Neuroscience · Aug 23, 2021Peer-reviewedNeuroscience

Alterations in retrotransposition, synaptic connectivity, and myelination implicated by transcriptomic changes following maternal immune activation in non-human primates

Nicholas F. Page, Michael J. Gandal, Myka L. Estes, Scott Cameron, Jessie E. Buth, Sepideh Parhami, Gokul Ramaswami, Karl D. Murray, David G. Amaral, Judy Van de Water, Cynthia Mills Schumann, Cameron S. Carter, Melissa D. Bauman, A. Kimberley McAllister, Daniel H. Geschwind

This study identifies transcriptomic changes in non-human primate brains exposed to maternal immune activation, revealing alterations in retrotransposition, synaptic connectivity, and myelination.

Biological Psychiatry · Nov 2, 2020Peer-reviewedNeuroscience

TGFβ superfamily signaling regulates the state of human stem cell pluripotency and competency to create telencephalic organoids

Momoko Watanabe, Jillian R. Haney, Neda Vishlaghi, Felix Turcios, Jessie E. Buth, Wen Gu, Amanda J. Collier, Osvaldo A. Miranda, Di Chen, Shan Sabri, Amander T. Clark, Kathrin Plath, Heather R. Christofk, Michael J. Gandal, Bennett G. Novitch

This study shows that maintaining human pluripotent stem cells with feeders improves cortical organoid formation by activating TGFβ signaling and naive pluripotency genes, which can be mimicked with TGFβ growth factors.

bioRxiv · Dec 13, 2019 · PreprintDevelopmental Biology