A molecularly defined basalo-prefrontal-thalamic circuit regulates sensory and affective dimensions of pain in male mice
Guoguang Xie, Yiqiong Liu, Xuetao Qi, Aritra Bhattacherjee, Chao Zhang, Yi Zhang
This study identifies a circuit involving mPFC Foxp2+ neurons that modulates sensory and affective pain in male mice, with therapeutic implications for chronic pain.
Nature Communications · Jan 29, 2026Peer-reviewedNeuroscience