Spatial transcriptomics for gene discovery identifies Slc13a5 as a modulator of bone mechanoadaptation
Quentin A Meslier, Alec T Beeve, Arushi Gupta, Daniel Palomo, Samia Saleem, Serena Eck, Lisa Y. Lawson, John T. Shuster, Michelle Brennan, Naomi Dirckx, Matthew J. Silva, Erica L. Scheller
This study uses spatial transcriptomics to identify Slc13a5 as a regulator of bone mechanoadaptation, showing its role in mineralization and resorption under mechanical loading.
bioRxiv · Mar 13, 2026 · PreprintBioengineering