Lisa Y. Lawson

This study uses spatial transcriptomics to identify Slc13a5 as a regulator of bone mechanoadaptation, showing its role in mineralization and resorption under mechanical loading.

This study shows that combining Sclerostin and Dkk1 antibodies with mechanical loading significantly enhances bone formation in aged mice.

This study shows that osteoblast-specific Wnt secretion is essential for maintaining bone homeostasis and the anabolic response to mechanical loading in adult mice.