Author

Ashu Chawla

La Jolla Institute for Immunology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:scRNA-seq· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Aruna Dharshan De SilvaiD· 3 shared Bjoern PetersiD· 3 shared Cecilia S. Lindestam ArlehamniD· 3 shared Julie G. BureliD· 3 shared Rashmi TippalagamaiD· 3 shared Thomas J. ScribaiD· 3 shared Alessandro SetteiD· 2 shared Darsha D. Senevirathne· 2 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Aruna Dharshan De SilvaORCID

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3 papers

Recent·Most cited

Enrichment of a CD4-CD8- NK-like cytotoxic Vδ1/3 T cell subset in tuberculosis disease

Kendall Kearns, Rashmi Tippalagama, Ashu Chawla, Jason Greenbaum, Aruna Dharshan De Silva, Wathsala Gunasinghe, Judy Perera, Hansani Gunasekera, Darsha D. Senevirathne, Thomas J. Scriba, Julie G. Burel, Cecilia S. Lindestam Arlehamn, Bjoern Peters

This study identifies an enriched NK-like cytotoxic Vδ3 T cell subset in TB patients using single-cell RNA sequencing, showing persistent transcriptomic differences post-treatment.

bioRxiv · Nov 12, 2025 · PreprintImmunology

A novel method for characterizing cell-cell interactions at single-cell resolution reveals unique signatures in blood T cell-monocyte complexes during infection

Ningxin Kang, Ashu Chawla, Hannah Hillman, Rashmi Tippalagama, Cheryl Kim, Zbigniew Mikulski, Sara McArdle, Grégory Seumois, Pandurangan Vijayanand, Thomas J. Scriba, Aruna Dharshan De Silva, Ángel Balmaseda, Eva Harris, Daniela Weiskopf, Alessandro Sette, , Julie G. Burel

The paper introduces a method to study cell-cell interactions at single-cell resolution, revealing unique transcriptomic signatures in T cell-monocyte complexes during TB and dengue infection.

iScience · Aug 23, 2025Peer-reviewedImmunology

Peptide Driven Identification of TCRs (PDI-TCR) reveals dynamics and phenotypes of CD4 T cells in tuberculosis

Rashmi Tippalagama, Raphael Trevizani, Leila Y. Chihab, Ashu Chawla, Kai Fung, Jason Greenbaum, Kendall Kearns, Aruna Dharshan De Silva, Wathsala Gunasinghe, Judy Perera, Hansani Gunasekera, Darsha D. Senevirathne, Thomas J. Scriba, Alessandro Sette, Cecilia S. Lindestam Arlehamn, , Bjoern Peters

PDI-TCR identifies Mtb-specific TCRs and characterizes their phenotypes in TB patients and healthy individuals, revealing distinct dynamics of specific and unspecific T cell responses.

bioRxiv · May 6, 2025 · PreprintImmunology