Bulk and single-cell gene expression profiling of SARS-CoV-2 infected human cell lines identifies molecular targets for therapeutic intervention
Emanuel Wyler, Kirstin Mösbauer, Vedran Franke, Asija Diag, Lina Theresa Gottula, Roberto Arsiè, Filippos Klironomos, David Koppstein, Katja Hönzke, Salah Ayoub, Christopher Buccitelli, Karen Hoffmann, Anja M. Richter, Ivano Legnini, Andranik Ivanov, , Markus Landthaler
The paper uses bulk and single-cell transcriptomics to analyze SARS-CoV-2 infection in human cell lines, identifying HSP90 as a potential therapeutic target.
iScience · Feb 7, 2021Peer-reviewedSystems Biology