Marcel Schilling

Quantification of transcript isoforms at the single-cell level using SCALPEL

SCALPEL quantifies single-cell transcript isoforms with higher sensitivity than existing tools, revealing novel cell populations and isoform regulation in mouse spermatogenesis and iPSC differentiation.

Identification of lncRNAs differentially expressed in Alzheimer's disease brains using RNA sequencing

The paper identifies differentially expressed lncRNAs in Alzheimer's disease brains using RNA-seq data from multiple studies and brain regions.

Genome-wide QTL mapping across three tissues highlights several Alzheimer's and Parkinson's disease loci potentially acting via DNA methylation

The paper maps DNA methylation quantitative trait loci (meQTL) in three tissues and uses Mendelian randomization to link DNAm to Alzheimer's and Parkinson's disease risk.

Entorhinal cortex epigenome-wide association study highlights four novel loci showing differential methylation in Alzheimer's disease

This study identifies four novel DNA methylation loci in the entorhinal cortex associated with Alzheimer's disease and finds significant epigenetic age acceleration in patients.

Common signatures of differential microRNA expression in Parkinson's and Alzheimer's disease brains

The paper assesses differential microRNA expression in Parkinson's and Alzheimer's disease brains, identifying shared miRNAs with potential pathogenic roles.

Differential microRNA expression analyses across two brain regions in Alzheimer's disease

The paper identifies differentially expressed miRNAs in two brain regions of Alzheimer's patients using qPCR and RNA-seq, highlighting potential targets involved in AD pathogenesis.

Regulation of spatial and temporal gene expression in an animal germline

The paper maps RNA expression in C. elegans germline using cryo-cutting, identifies miRNAs and differential 3 UTR usage, and proposes regulatory mechanisms for spatial gene expression.