Single-cell, spatial, and fate-mapping analyses uncover niche dependent diversity of cochlear myeloid cells.
Aude Chiot, Max J. Felgner, Dillon Brownell, Katherine H. Rott, Alina P. Bogachuk, Dennis-Dominik Rosmus, Takahiro Masuda, Audrey Ching, Patrick J. Atkinson, Marco Prinz, Karen Sachs, Alan Gi-Lun Cheng, Peter Wieghofer, Bahareh Ajami
This study identifies five myeloid cell types in the mouse cochlea using single-cell transcriptomics, fate mapping, and parabiosis, revealing their spatial distribution, ontogeny, and functional diversity.
bioRxiv · Oct 30, 2024 · PreprintImmunology