Katherine H. Rott

This study maps human pulmonary T-cell immunity across TB infection/disease using single-cell transcriptomics and functional T-cell cloning, identifying protective immune features and a platform for TB vaccine development.

This study examines how BCG vaccination at birth affects MR1T cell TCR usage and function in infants, finding increased type I interferon response and a TCR cluster enriched in vaccinated infants.

This study compares neonatal and adult MR1T cells, finding neonatal cells have diverse TCR usage, reduced cytotoxicity, and limited pathogen recognition.

This study identifies five myeloid cell types in the mouse cochlea using single-cell transcriptomics, fate mapping, and parabiosis, revealing their spatial distribution, ontogeny, and functional diversity.