Author

Autumn O Grimins

Boston University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1

Frequent Co-Authors

Assen MarintcheviD· 2 shared Mohsan SaeediD· 2 shared Mollie A. BrekkeriD· 2 shared Ryan Johnston· 2 shared Sami Gritli· 2 shared Shawn M. LyonsiD· 2 shared Alan WacquieziD· 1 shared Anne Aldrich· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersMolecular Biology

Assen MarintchevORCID

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2 papers

Recent·Most cited

eIF4E3 drives translation of viral mRNAs with short 5' UTRs

Autumn O Grimins, Mollie A. Brekker, Sarah Ruth Shick, Ellen L. Suder, Victoria A. Kleiner, Sami Gritli, Ryan Johnston, Alan Wacquiez, Mohsan Saeed, Assen Marintchev, Elke Mühlberger, Rachel Fearns, John H. Connor, Shawn M. Lyons

The paper shows eIF4E3 enables efficient translation of viral mRNAs with short 5' UTRs, unlike the canonical eIF4E1, and identifies this as a mechanism used by viruses like VSV to bypass host translation suppression.

bioRxiv · May 26, 2026 · PreprintMolecular Biology

Proteolytic dissection of eIF4G reveals the closed-loop mRNP as an architecture for translation repression.

Ryan Johnston, Mollie A. Brekker, Noelle Khalil, Monty E. Goldstein, Anne Aldrich, Autumn O Grimins, Sami Gritli, Assen Marintchev, Michael D. Blower, Mohsan Saeed, Shawn M. Lyons

The paper shows that eIF4G cleavage products can either rescue or repress translation, revealing the closed-loop mRNP's role in translational silencing rather than initiation.

bioRxiv · Apr 7, 2026 · PreprintMolecular Biology