Author

B. B. Larsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Organism:human· 2 Research Focus:phylogenetics / evolution· 2 Organism:rat· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

M. Worobey· 4 shared S. Gryseels· 4 shared H. W. Otto· 2 shared A. Varsani· 1 shared C. E. Radford· 1 shared C. Richet· 1 shared D. E. Teuwen· 1 shared D. Veesler· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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4 shared papersEvolutionary Biology

M. Worobey

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Author profile →

5 papers

Recent·Most cited

Functional and antigenic landscape of the Nipah virus receptor binding protein

B. B. Larsen, T. McMahon, J. T. Brown, Z. Wang, C. E. Radford, J. E. Crowe, D. Veesler, J. D. Bloom

This study uses deep mutational scanning to analyze how mutations in the Nipah virus receptor-binding protein affect function, receptor binding, and antibody escape, revealing constrained regions and limited antigenic variation in natural strains.

Cell · May 1, 2025Peer-reviewedEvolutionary Biology

Isolation and Divergence of Peromyscus melanotis Populations Across the Madrean Sky Islands in Arizona

B. B. Larsen, H. W. Otto, S. Gryseels, M. Worobey

The paper identifies Peromyscus melanotis in Arizona's sky islands and estimates their isolation duration using mitochondrial data.

bioRxiv · Apr 11, 2022 · PreprintEvolutionary Biology

Evolution and diversity of bat and rodent Paramyxoviruses from North America

B. B. Larsen, S. Gryseels, H. W. Otto, M. Worobey

The paper characterizes paramyxovirus diversity in North American bats and rodents, identifying two rodent clades and one bat clade, and infers receptor binding patterns.

bioRxiv · Jul 1, 2021Evolutionary Biology

Co-evolutionary analysis suggests a role for TLR9 in papillomavirus restriction

K. M. King, B. B. Larsen, S. Gryseels, C. Richet, S. Kraberger, R. Jackson, M. Worobey, J. S. Harrison, A. Varsani, K. Van Doorslaer

This study identifies TLR9 as a pattern recognition receptor involved in detecting papillomaviruses and shows co-evolution between papillomaviruses and their hosts.

bioRxiv · Apr 17, 2021 · PreprintMicrobiology

A near-full-length HIV-1 genome from 1966 recovered from formalin-fixed paraffin-embedded tissue

S. Gryseels, T. D. Watts, J.-M. M. Kabongo, B. B. Larsen, P. Lemey, J.-J. Muyembe-Tamfum, D. E. Teuwen, M. Worobey

The paper recovers a near-full-length HIV-1 genome from 1966, validating molecular clock estimates and providing direct genomic evidence for HIV-1 evolution in the 1960s.

bioRxiv · Jul 1, 2019Evolutionary Biology