Author

B. C. Lin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:non-human primate· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

A. Dodson· 2 shared A. R. Henry· 2 shared A. Van Ry· 2 shared B. J. Flynn· 2 shared D. R. Flebbe· 2 shared F. Laboune· 2 shared I.-T. Teng· 2 shared J.-P. M. Todd· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

A. Dodson

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Author profile →

4 papers

Recent·Most cited

Mucosal Adenoviral-vectored Vaccine Boosting Durably Prevents XBB.1.16 Infection in Nonhuman Primates

M. Gagne, B. J. Flynn, S. F. Andrew, D. R. Flebbe, A. Mychalowych, E. Lamb, M. E. Davis-Gardner, M. R. Burnett, L. A. Serebryannyy, B. C. Lin, L. Pessaint, J.-P. M. Todd, Z. E. Ziff, E. Maule, R. Carroll, , M Suthar

This study shows that mucosal adenoviral-vectored vaccines provide durable protection against XBB.1.16 infection in nonhuman primates, outperforming intramuscular boosting in reducing virus replication in both upper and lower airways.

bioRxiv · Nov 6, 2023 · PreprintImmunology

mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits comparable B cell expansion, neutralizing antibodies and protection against Omicron

M. Gagne, J. I. Moliva, K. E. Foulds, S. F. Andrew, B. J. Flynn, A. P. Werner, D. A. Wagner, I.-T. Teng, B. C. Lin, C. Moore, N. Jean-Baptiste, R. Carroll, S. L. Foster, M. Patel, M. Ellis, , Naisan

This study compares B cell responses and protection against Omicron after boosting vaccinated macaques with mRNA-1273 or mRNA-Omicron vaccines, finding comparable immunity and protection.

bioRxiv · Feb 3, 2022 · PreprintImmunology

Rapid selection of HIV envelopes that bind to neutralizing antibody B cell lineage members with functional improbable mutations

O. Swanson, B. Rhodes, A. Wang, X. Shi-Mao, R. Parks, A. Sanzone, M. K. Louder, B. C. Lin, N. Doria-Rose, M. Bonsignori, K. O. Saunders, K. Wiehe, B. F. Haynes, M. L. Azoitei

The paper identifies a minimal set of mutations required for the function of a HIV bnAb and demonstrates in vitro selection of envelope immunogens that can bind to antibodies with these mutations.

bioRxiv · Jan 4, 2021Immunology

Recapitulation of HIV-1 Env-Antibody Coevolution in Macaques Leading to Neutralization Breadth

R. S. Roark, H. Li, W. B. Williams, H. Chug, R. D. Mason, J. Gorman, S. Wang, F.-H. Lee, J. Rando, M. Bonsignori, K.-K. Hwang, K. O. Saunders, K. Wiehe, M. A. Moody, P. T. Hraber, , C. A Schramm

Virus-antibody coevolution in rhesus macaques recapitulates developmental features of human antibodies.

bioRxiv · Aug 5, 2020Immunology