J. Chakraborty

Related PP2C phosphatases Pic3 and Pic12 negatively regulate immunity in tomato to Pseudomonas syringae

This study identifies Pic3 and Pic12 as PP2C phosphatases that negatively regulate tomato immunity against Pseudomonas syringae through flagellin-independent pathways.

Structural Requirements for Reverse Transcription by a Diversity-generating Retroelement

This study identifies how surrounding RNA structures facilitate reverse transcription in DGRs by positioning an RNA homoduplex for cis-priming and regulating mutagenesis.

Efficient Prohibitin 2 exposure during mitophagy depends on Voltage-dependent anion-selective channel protein 1.

This study shows that VDAC1 enhances PHB2 exposure and mitophagy efficiency during mitochondrial depolarization in Drosophila.

An amphipathic helix facilitates direct membrane binding of Mycoplasma FtsZ

This study identifies a novel amphipathic helix in mycoplasma FtsZ that enables direct membrane binding, offering insights into Z-ring constriction in cell wall-less bacteria.

Activation of Ca2+ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy

This study identifies Calcineurin as a regulator of Parkin translocation to mitochondria and mitophagy, showing its role in both basal and stress-induced processes.

Dynamics of interdomain rotation facilitates FtsZ filament assembly

This study investigates FtsZ assembly dynamics by analyzing SmFtsZ from Spiroplasma melliferum, showing that interdomain rotation is a rate-limiting step in polymerization.

A salt bridge-mediated resistance mechanism to FtsZ inhibitor PC190723 revealed by a cell-based screen

This paper develops a cell-based assay to screen for FtsZ inhibitors and identifies a salt bridge-mediated resistance mechanism to PC190723 in Helicobacter pylori FtsZ.