Author

B. Hoang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2

Frequent Co-Authors

A. Ferrena· 2 shared D. Geller· 2 shared D. Zheng· 2 shared E. Schwartz· 2 shared H. Borjihan· 2 shared H. Zhao· 2 shared J. Wang· 2 shared R. Yang· 2 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCancer Biology

A. Ferrena

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Comprehensive single cell transcriptomics analysis of murine osteosarcoma uncovers Skp2 function in metastasis, genomic instability and immune activation and reveals additional target pathways

A. Ferrena, R. Zhang, J. Wang, X. Y. Zheng, B. Goker, H. Borjihan, S.-S. Chae, Y. Lo, H. Zhao, E. Schwartz, D. Loeb, R. Yang, D. Geller, D. Zheng, B. Hoang

This study uses scRNA-seq to analyze murine osteosarcoma models and identifies Skp2's role in metastasis, genomic instability, and immune activation, revealing potential therapeutic targets.

bioRxiv · Jun 4, 2024 · PreprintCancer Biology

Immunosuppressive tumor microenvironment of osteosarcoma

A. M. Taylor, J. Sheng, P. K. S. Ng, J. M. Harder, P. Kumar, J. Y. Ahn, Y. Cao, A. M. Dzis, N. L. Jillette, A. Goodspeed, A. Bodlak, Q. Wu, M. S. Isakoff, J. George, J. D. S. Grassman, , C. C. Lau

This study identifies immunosuppressive mechanisms in osteosarcoma using single-cell and spatial transcriptomics, revealing interactions between MDSCs, T-cells, and tumor cells that promote an immunosuppressive microenvironment.

bioRxiv · Nov 1, 2023Cancer Biology

SKP2 knockout in Rb1/p53 deficient mouse models of osteosarcoma induces immune infiltration and drives a transcriptional program with a favorable prognosis

A. Ferrena, J. Wang, R. Zhang, B. Karadal-Ferrena, W. al-Hardan, S. Singh, H. Borjihan, E. Schwartz, H. Zhao, R. Yang, D. Geller, B. Hoang, D. Zheng

This study shows SKP2 knockout in osteosarcoma mouse models increases immune infiltration and correlates with improved patient survival.

bioRxiv · May 9, 2023Cancer Biology

Characterization of the DNA binding domain of StbA, a key protein of a new type of DNA segregation system

V. Quebre, I. del Campo, A. Cuevas, P. Siguier, J. Rech, L. Phan Thai Nguyen, b. hoang, F. Cornet, j.-y. bouet, G. Moncalian, F. de la Cruz, C. Guynet

This study determines the crystal structure of the N-terminal DNA-binding domain of StbA, revealing its HTH motif and role in plasmid segregation and transcription repression.

bioRxiv · Apr 29, 2022Microbiology