F. de la Cruz

The paper identifies two key parameters governing plasmid transmission dynamics and shows they are characteristic of the plasmid transfer machinery.

This study determines the crystal structure of the N-terminal DNA-binding domain of StbA, revealing its HTH motif and role in plasmid segregation and transcription repression.

This study examines how plasmid mobility evolves by analyzing gene repertoires and relaxases, finding that mobility transitions are linked to significant gene changes and the emergence of new plasmid types.

The paper shows ArdC protein enables plasmid conjugation from E. coli to Pseudomonas putida by counteracting the hsdRMS restriction system, and reveals its structural and functional properties.

The paper compares MOBQ4 plasmids, showing they are a cis-acting-enriched relaxase family that can coexist and transfer efficiently with helper plasmids.

The paper compares integrative and extrachromosomal mobile genetic elements to explain their co-existence through differences in genetic plasticity and host range.

The paper introduces ResCap, a targeted metagenomics platform for analyzing resistomes, enhancing sensitivity and specificity in detecting antimicrobial resistance genes.