Author

A. M. Taylor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. A. Lakhani· 1 shared A. Bodlak· 1 shared A. D. Lindsay· 1 shared A. Didomizio· 1 shared A. Goodspeed· 1 shared A. L. Manning· 1 shared A. M. Dzis· 1 shared A. S. Petrilli· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCancer Biology

A. A. Lakhani

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Author profile →

5 papers

Recent·Most cited

Immunosuppressive tumor microenvironment of osteosarcoma

A. M. Taylor, J. Sheng, P. K. S. Ng, J. M. Harder, P. Kumar, J. Y. Ahn, Y. Cao, A. M. Dzis, N. L. Jillette, A. Goodspeed, A. Bodlak, Q. Wu, M. S. Isakoff, J. George, J. D. S. Grassman, , C. C. Lau

This study identifies immunosuppressive mechanisms in osteosarcoma using single-cell and spatial transcriptomics, revealing interactions between MDSCs, T-cells, and tumor cells that promote an immunosuppressive microenvironment.

bioRxiv · Nov 1, 2023Cancer Biology

"Important enough to show the world": Using Authentic Research Opportunities and Micropublications to Build Students Science Identities

L. D. Rubenstein, K. A. Woodruff, A. M. Taylor, J. B. Olesen, P. J. Smaldino, E. M. Rubenstein

This study explores how micropublications and authentic research opportunities help undergraduate and master's students develop scientific competencies and identities.

bioRxiv · Aug 17, 2023Scientific Communication & Education

Oncogene-like addiction to aneuploidy in human cancers

V. Girish, A. A. Lakhani, C. M. Scaduto, S. L. Thompson, L. M. Brown, R. A. Hagenson, E. L. Sausville, B. E. Mendelson, D. A. Lukow, M. L. Yuan, P. K. Kandikuppa, E. C. Stevens, S. N. Lee, B. Salovska, W. Li, , J. M. Sheltzer

This study demonstrates that trisomy of chromosome 1q is essential for malignant growth in cancers and shows that TP53 mutations are mutually exclusive with 1q aneuploidy.

bioRxiv · Jan 9, 2023Cancer Biology

Ing4-deficiency enhances HSC quiescence and confers resistance to inflammatory stress

Z. Thompson, G. A. Anderson, M. Rodriguez, S. Gabriel, V. Binder, A. M. Taylor, K. L. Kathrein

This study shows that Ing4 deficiency increases HSC quiescence and protects against inflammatory stress by altering gene expression and cell cycle dynamics.

bioRxiv · Jul 14, 2021 · PreprintCell Biology

Whole genome doubling confers unique genetic vulnerabilities on tumor cells

R. J. Quinton, A. Didomizio, M. A. Vittoria, C. J. Ticas, S. Patel, Y. Koga, K. Kotynkova, J. Vakhshoorzadeh, N. Hermance, T. S. Kuroda, N. Parulekar, A. M. Taylor, A. L. Manning, J. D. Campbell, N. J. Ganem

The paper identifies genetic vulnerabilities in WGD+ tumor cells and shows that KIF18A is specifically required for their viability.

bioRxiv · Jun 18, 2020Cancer Biology