Author

B. Houck-Loomis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Chow· 2 shared A. Quintanal-Villalonga· 2 shared C. M. Rudin· 2 shared E. de Stanchina· 2 shared F. Meng· 2 shared F. Uddin· 2 shared J. M. Chan· 2 shared T. Sen· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

A. Chow

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ERα-LBD, a novel isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance

A. Strillacci, P. Sansone, V. R. Rajasekhar, M. Turkekul, V. Boyko, F. Meng, B. Houck-Loomis, D. Brown, M. F. Berger, R. C. Hendrickson, Q. Chang, E. de Stanchina, F. Pareja, J. S. Reis-Filho, R. Segu Rajappachetty, , J. Bromberg

The paper identifies ER-LBD, a novel estrogen receptor alpha isoform, which promotes breast cancer growth and resistance to endocrine therapy.

bioRxiv · Oct 14, 2021 · PreprintCancer Biology

Regional and clonal T cell dynamics at single cell resolution in immune checkpoint blockade

J. A. Pai, A. Chow, J. Sauter, M. Mattar, H. Rizvi, H. J. Woo, N. Shah, F. Uddin, A. Quintanal-Villalonga, J. M. Chan, P. Manoj, V. Allaj, M. Baine, J. E. Chaft, A. J. Plodkowski, , M. D. Hellmann

This study uses scTCR/RNA-seq to analyze T cell dynamics in lung cancer patients before and after ICB, finding regional heterogeneity and clonal persistence associated with clinical responses.

bioRxiv · Sep 27, 2021 · PreprintImmunology

Multi-omic analysis of lung tumors defines pathways activated in neuroendocrine transformation

A. Quintanal-Villalonga, H. Taniguchi, M. A. Hasan, F. Meng, F. Uddin, M. Donoghue, H. H. Won, S. S. Chavan, J. M. Chan, M. Ciampricotti, A. Chow, M. Offin, J. C. Chang, J. Ray-Kirton, J. Egger, , T. Sen

The paper identifies molecular mechanisms of neuroendocrine transformation in lung cancer using multi-omic analysis of tumors and clinical samples.

bioRxiv · Dec 2, 2020 · PreprintCancer Biology