Author

B. J. Geiss

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Approach:mechanistic / dynamical model· 2 Research Focus:protein folding & dynamics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

M. McCullagh· 3 shared G. D. Ebel· 2 shared N. R. Sexton· 2 shared T. Schountz· 2 shared A. Fagre· 1 shared B. Burke· 1 shared C. E. McAlister· 1 shared J. Hendrix· 1 shared

Activity by Year

2019-2020 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

M. McCullagh

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A Hyperactive Kunjin Virus NS3 Helicase Mutant Demonstrates Increased Dissemination and Mortality in Mosquitoes

K. E. Du Pont, N. R. Sexton, M. McCullagh, G. D. Ebel, B. J. Geiss

This study investigates the role of NS3 Motif V mutations in Kunjin virus replication and pathogenesis, finding that S411A mutant increases viral dissemination and mortality in mosquitoes.

Journal of Virology · Sep 15, 2020Peer-reviewedMicrobiology

Development of SARS-CoV-2 Nucleocapsid Specific Monoclonal Antibodies

J. S. Terry, L. B. Anderson, M. S. Scherman, C. E. McAlister, R. Perera, T. Schountz, B. J. Geiss

This study develops and characterizes mouse monoclonal antibodies specific to SARS-CoV-2 nucleocapsid protein, tested using ELISA, western blot, and immunofluorescence.

bioRxiv · Sep 3, 2020Microbiology

SARS-CoV-2 infection, neuropathogenesis and transmission among deer mice: Implications for reverse zoonosis to New World rodents

A. Fagre, J. Lewis, M. Eckley, S. Zhan, S. M. Rocha, N. R. Sexton, B. Burke, B. J. Geiss, O. Peersen, R. Kading, J. Rovnak, G. D. Ebel, R. B. Tjalkens, T. Aboellail, T. Schountz

This study infects deer mice with SARS-CoV-2, showing robust replication and potential for natural transmission, with a new spike protein mutation emerging during in vivo passage.

bioRxiv · Aug 7, 2020Microbiology

RNA-dependent structures of the RNA-binding loop in the flavivirus NS3 helicase

R. B. Davidson, J. Hendrix, B. J. Geiss, M. McCullagh

This study investigates the RNA-dependent structural dynamics of the flavivirus NS3 helicase RNA-binding loop using molecular dynamics simulations, revealing how RNA binding stabilizes specific conformations and impacts NTPase activity.

bioRxiv · Jan 15, 2020Biophysics

Motif V acts as a Regulator of Energy Transduction Between the Flavivirus NS3 ATPase and RNA Binding Cleft

K. E. DuPont, R. Davidson, M. McCullagh, B. J. Geiss

This study investigates the role of Motif V in NS3 helicase energy transduction, finding that mutations increase dsRNA unwinding rates and alter structural communication between ATP and RNA binding sites.

bioRxiv · Nov 14, 2019Biochemistry