G. D. Ebel

Phagocyte-expressed glycosaminoglycans promote capture of alphaviruses from the blood circulation in a host species-specific manner.

This study shows that phagocyte-expressed glycosaminoglycans mediate species-specific vascular clearance of alphaviruses, with some viruses being cleared faster than others.

North American Powassan virus encompasses diverse in vitro phenotypes.

This study examines in vitro phenotypic diversity of North American Powassan virus isolates and finds broad differences in replication and cytopathic ability unrelated to geographic or temporal origin or specific genotypes.

Strain-dependent assessment of Powassan virus transmission to deer ticks.

The paper assesses strain-dependent transmission of Powassan virus to deer ticks and finds no significant differences in infection rates or viral load across five isolates.

Semi-field and surveillance data define the natural diapause timeline for Culex pipiens across the United States

The paper uses surveillance data to define the diapause timeline for Culex pipiens across the U.S., showing population declines during diapause receptivity and highlighting genetic factors affecting population trends.

Impact of prior infection on SARS-CoV-2 antibody responses in vaccinated long-term care facility staff

This study examines how prior SARS-CoV-2 infection affects antibody responses to vaccination in long-term care facility staff, finding higher antibody levels in previously infected individuals and no booster response in those with prior immunity.

Genomic and phenotypic analyses suggest moderate fitness differences among Zika virus lineages

The paper analyzes genomic and phenotypic data from Zika virus lineages to assess fitness differences during the 2015-2016 epidemic, finding moderate fitness changes but no significant virulence or transmission enhancement.

Durable antibody responses in staff at two long-term care facilities, during and post SARS-CoV-2 outbreaks

The paper examines antibody responses in long-term care facility staff during and after SARS-CoV-2 outbreaks, finding durable neutralizing antibodies and potential herd immunity.

Rapid evolution of enhanced Zika virus virulence during direct vertebrate transmission chains

This study shows ZIKV adapts more rapidly to mice during direct transmission compared to mosquito or alternating host transmission, with a virulence-enhancing mutation emerging.

A Hyperactive Kunjin Virus NS3 Helicase Mutant Demonstrates Increased Dissemination and Mortality in Mosquitoes

This study investigates the role of NS3 Motif V mutations in Kunjin virus replication and pathogenesis, finding that S411A mutant increases viral dissemination and mortality in mosquitoes.

SARS-CoV-2 infection, neuropathogenesis and transmission among deer mice: Implications for reverse zoonosis to New World rodents

This study infects deer mice with SARS-CoV-2, showing robust replication and potential for natural transmission, with a new spike protein mutation emerging during in vivo passage.

A reverse-transcription/RNase H based protocol for depletion of mosquito ribosomal RNA facilitates viral intrahost evolution analysis, transcriptomics and pathogen discovery.

This paper introduces a reverse-transcription/RNase H protocol to deplete mosquito rRNA, enabling efficient viral analysis and discovery in field samples.

Adventitious viruses persistently infect three commonly used mosquito cell lines

The paper identifies persistent viral infections in four commonly used mosquito cell lines, showing that they harbor active viral replication and integration.

Molecularly barcoded Zika virus libraries to probe in vivo evolutionary dynamics

This paper uses molecularly barcoded Zika virus to study in vivo infection dynamics in pregnant and non-pregnant macaques and mosquitoes, finding stable lineage proportions during acute infection but a rapid decline in complexity post-infection in pregnant animals.