Author

M. Eckley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

S. Zhan· 4 shared T. Schountz· 4 shared J. Lewis· 3 shared A. Fagre· 2 shared B. Burke· 2 shared R. B. Tjalkens· 2 shared S. M. Rocha· 2 shared T. Aboellail· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersMicrobiology

S. Zhan

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Author profile →

4 papers

Recent·Most cited

Regulatory T Cell-like Response to SARS-CoV-2 in Jamaican Fruit Bats Transduced with Human ACE2

B. Burke, S. Rocha, S. Zhan, M. Eckley, C. Reasoner, A. Addetia, J. Lewis, A. C. Fagre, P. Charley, J. A. Richt, S. R. Weiss, R. Tjalkens, D. Veesler, T. Aboellail, T. Schountz

This study shows Jamaican fruit bats are poorly susceptible to SARS-CoV-2 but develop a regulatory T cell-like immune response when transduced with human ACE2, leading to lung infection without overt disease.

bioRxiv · Feb 13, 2023Microbiology

Assessing the zoonotic potential of a novel bat morbillivirus

S. Ikegame, J. C. Carmichael, H. Wells, R. L. Furler O'Brien, J. A. Acklin, H.-P. Chiu, K. Y. Oguntuyo, R. M. Cox, A. R. Patel, S. Kowdle, C. S. Stevens, M. Eckley, S. Zhan, J. K. Lim, E. C. Veit, , B. Lee

This study identifies a novel bat morbillivirus, MBaMV, and assesses its zoonotic potential by showing it can infect human cells but is restricted by human immune responses.

bioRxiv · Sep 17, 2021 · PreprintMicrobiology

A potent SARS-CoV-2 neutralizing human monoclonal antibody that reduces viral burden and disease severity in Syrian hamsters

A. Fagre, J. Manhard, R. Adams, M. Eckley, S. Zhan, J. Lewis, S. M. Rocha, C. Woods, K. Kuo, W. Liao, L. Li, A. Corper, D. Challa, E. Mount, C. Tumanut, , T. Schountz

bioRxiv · Sep 25, 2020Microbiology

SARS-CoV-2 infection, neuropathogenesis and transmission among deer mice: Implications for reverse zoonosis to New World rodents

A. Fagre, J. Lewis, M. Eckley, S. Zhan, S. M. Rocha, N. R. Sexton, B. Burke, B. J. Geiss, O. Peersen, R. Kading, J. Rovnak, G. D. Ebel, R. B. Tjalkens, T. Aboellail, T. Schountz

This study infects deer mice with SARS-CoV-2, showing robust replication and potential for natural transmission, with a new spike protein mutation emerging during in vivo passage.

bioRxiv · Aug 7, 2020Microbiology