Author

O. Peersen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Organism:mouse· 1

Frequent Co-Authors

A. Fagre· 1 shared A. Shannon· 1 shared B. Burke· 1 shared B. Canard· 1 shared B. Coutard· 1 shared B. J. Geiss· 1 shared B. J. Kempf· 1 shared B. Selisko· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperMicrobiology

A. Fagre

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

SARS-CoV-2 infection, neuropathogenesis and transmission among deer mice: Implications for reverse zoonosis to New World rodents

A. Fagre, J. Lewis, M. Eckley, S. Zhan, S. M. Rocha, N. R. Sexton, B. Burke, B. J. Geiss, O. Peersen, R. Kading, J. Rovnak, G. D. Ebel, R. B. Tjalkens, T. Aboellail, T. Schountz

This study infects deer mice with SARS-CoV-2, showing robust replication and potential for natural transmission, with a new spike protein mutation emerging during in vivo passage.

bioRxiv · Aug 7, 2020Microbiology

Favipiravir strikes the SARS-CoV-2 at its Achilles heel, the RNA polymerase

A. Shannon, B. Selisko, T.-T.-N. Le, J. Huchting, F. Touret, G. Piorkowski, V. Fattorini, F. Ferron, E. Decroly, C. Meier, B. Coutard, O. Peersen, B. Canard

This study shows Favipiravir inhibits SARS-CoV-2 by targeting its RNA polymerase through chain termination, slowed synthesis, and mutagenesis.

bioRxiv · May 15, 2020 · PreprintBiochemistry

An Extended Primer Grip of Picornavirus Polymerase Facilitates Sexual RNA Replication Mechanisms

B. J. Kempf, C. L. Watkins, O. Peersen, D. J. Barton

This study identifies polymerase mutations that facilitate sexual RNA replication in picornaviruses and shows how these mutations affect ribavirin resistance and RNA synthesis fidelity.

bioRxiv · Dec 13, 2019Microbiology